Metformin improves FOXP3 mRNA expression through suppression of interferon gamma levels in pristane-induced murine models of lupus [version 2; peer review: 2 approved]

Metformin improves FOXP3 mRNA expression through suppression of interferon gamma levels in pristane-induced murine models of lupus [version 2; peer review: 2 approved]

Background:  A recent study has indicated the potential of metformin therapy for lupus in animal models, but there has been no study evaluating the effect on pristane-induced lupus. This study aims to evaluate the effect of intraperitoneal versus oral metformin on interferon (IFN)-γ levels and FOXP3...

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Bibliographic Details
Main Authors: Stevent Sumantri, Mochammad Hatta, Rosdiana Natzir, Haerani Rasyid, Iris Rengganis, Muhammad Nasrum Massi, Andi Asadul Islam, Gatot Lawrence, Ilhamjaya Patellongi, Andi Fachruddin Benyamin
Format: Article
Language:English
Published: F1000 Research Ltd 2021-06-01
Series:F1000Research
Online Access:https://f1000research.com/articles/9-342/v2

Internet

https://f1000research.com/articles/9-342/v2

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