Possible Roles of IL-33 in the Innate-Adaptive Immune Crosstalk of Psoriasis Pathogenesis

Background. IL-33 belongs to the IL-1 family, playing a role in several biologic processes as well as in the pathogenesis of different diseases, including skin pathologies. It acts as an alarmin, released by damaged cells. Binding to a ST2 receptor, it stimulates many immune cells such as ILC2 and T...

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Bibliographic Details
Main Authors: Serafinella Patrizia Cannavò, Lucrezia Bertino, Eleonora Di Salvo, Valeria Papaianni, Elvira Ventura-Spagnolo, Sebastiano Gangemi
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/7158014