Punicalagin Attenuates Disturbed Flow-Induced Vascular Dysfunction by Inhibiting Force-Specific Activation of Smad1/5

Punicalagin Attenuates Disturbed Flow-Induced Vascular Dysfunction by Inhibiting Force-Specific Activation of Smad1/5

BackgroundPathophysiological vascular remodeling in response to disturbed flow with low and oscillatory shear stress (OSS) plays important roles in atherosclerosis progression. Pomegranate extraction (PE) was reported having anti-atherogenic effects. However, whether it can exert a beneficial effect...

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Bibliographic Details
Main Authors: Gulinigaer Anwaier, Guan Lian, Gui-Zhi Ma, Wan-Li Shen, Chih-I Lee, Pei-Ling Lee, Zhan-Ying Chang, Yun-Xia Wang, Xiao-Yu Tian, Xiao-Li Gao, Jeng-Jiann Chiu, Rong Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
pomegranate
punicalagin
oscillatory shear stress
atherosclerosis
endothelial cell
Smads
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.697539/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.697539/full

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