Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa
<p>Abstract</p> <p>The selection of point mutation at codon 164 (from isoleucine to leucine) of the dihydrofolate reductase (DHFR) enzyme in <it>Plasmodium falciparum </it>is associated with high sulfadoxine /pyrimethamine (SP) resistance. Using the yeast expression sys...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2003-12-01
|
| Series: | Malaria Journal |
| Online Access: | http://www.malariajournal.com/content/2/1/46 |