A short receptor downregulates JAK/STAT signalling to control the Drosophila cellular immune response.

The posterior signalling centre (PSC), a small group of specialised cells, controls hemocyte (blood cell) homeostasis in the Drosophila larval hematopoietic organ, the lymph gland. This role of the PSC is very reminiscent of the "niche," the micro-environment of hematopoietic stem cells in...

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Bibliographic Details
Main Authors: Rami Makki, Marie Meister, Delphine Pennetier, Jean-Michel Ubeda, Anne Braun, Virginie Daburon, Joanna Krzemień, Henri-Marc Bourbon, Rui Zhou, Alain Vincent, Michèle Crozatier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2914635?pdf=render