Identification of NUDT5 Inhibitors From Approved Drugs

Recent studies have revealed the important role of NUDT5 in estrogen signaling and breast cancer, but research on the corresponding targeted therapy has just started. Drug repositioning strategy can effectively reduce the time and economic resources spent on drug discovery. To find novel inhibitors...

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Bibliographic Details
Main Authors: Xin-Yu Tong, Xuan Liao, Min Gao, Bo-Min Lv, Xiao-Hui Chen, Xin-Yi Chu, Qing-Ye Zhang, Hong-Yu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.00044/full