Protein-protein interactions in paralogues: Electrostatics modulates specificity on a conserved steric scaffold.

An improved knowledge of protein-protein interactions is essential for better understanding of metabolic and signaling networks, and cellular function. Progress tends to be based on structure determination and predictions using known structures, along with computational methods based on evolutionary...

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Bibliographic Details
Main Authors: Stefan M Ivanov, Andrew Cawley, Roland G Huber, Peter J Bond, Jim Warwicker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5634604?pdf=render