Metformin Use Is Associated with Decreased Mortality in COVID-19 Patients with Diabetes: Evidence from Retrospective Studies and Biological Mechanism

Metformin Use Is Associated with Decreased Mortality in COVID-19 Patients with Diabetes: Evidence from Retrospective Studies and Biological Mechanism

Background and Aims: The coronavirus disease 2019 (COVID-19) increases hyperinflammatory state, leading to acute lung damage, hyperglycemia, vascular endothelial damage, and a higher mortality rate. Metformin is a first-line treatment for type 2 diabetes and is known to have anti-inflammatory and im...

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Bibliographic Details
Main Authors: Tahmina Nasrin Poly, Md. Mohaimenul Islam, Yu-Chuan (Jack) Li, Ming-Chin Lin, Min-Huei Hsu, Yao-Chin Wang
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Clinical Medicine
Subjects:
metformin
diabetes
insulin
mortality
severity
COVID-19
Online Access:https://www.mdpi.com/2077-0383/10/16/3507

Internet

https://www.mdpi.com/2077-0383/10/16/3507

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