Coronavirus spike protein inhibits host cell translation by interaction with eIF3f.

In response to viral infection, the expression of numerous host genes, including predominantly a number of proinflammatory cytokines and chemokines, is usually up-regulated at both transcriptional and translational levels. It was noted that in cells infected with coronavirus, transcription and trans...

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Bibliographic Details
Main Authors: Han Xiao, Ling Hui Xu, Yoshiyuki Yamada, Ding Xiang Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2204050?pdf=render