Expression of Cyclins A, E and Topoisomerase II α correlates with centrosome amplification and genomic instability and influences the reliability of cytometric S-phase determination

<p>Abstract</p> <p>Background</p> <p>The progression of normal cells through the cell cycle is meticulously regulated by checkpoints guaranteeing the exact replication of the genome during S-phase and its equal division at mitosis. A prerequisite for this achievement is...

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Bibliographic Details
Main Authors: Laytragoon-Lewin Nongnit, Faridmoghaddam Farinaz, Östring Carin, Fujioka Kaoru, Roblick Uwe J, Castro Juan, Kronenwett Ulrike, Tribukait Bernhard, Auer Gert
Format: Article
Language:English
Published: BMC 2003-07-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/4/8