Expression of Cyclins A, E and Topoisomerase II α correlates with centrosome amplification and genomic instability and influences the reliability of cytometric S-phase determination
<p>Abstract</p> <p>Background</p> <p>The progression of normal cells through the cell cycle is meticulously regulated by checkpoints guaranteeing the exact replication of the genome during S-phase and its equal division at mitosis. A prerequisite for this achievement is...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2003-07-01
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Series: | BMC Cell Biology |
Online Access: | http://www.biomedcentral.com/1471-2121/4/8 |