Enhancement of cell-based therapeutic angiogenesis using a novel type of injectable scaffolds of hydroxyapatite-polymer nanocomposite microspheres.

BACKGROUND: Clinical trials demonstrate the effectiveness of cell-based therapeutic angiogenesis in patients with severe ischemic diseases; however, their success remains limited. Maintaining transplanted cells in place are expected to augment the cell-based therapeutic angiogenesis. We have reporte...

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Main Authors: Yohei Mima, Shinya Fukumoto, Hidenori Koyama, Masahiro Okada, Shinji Tanaka, Tetsuo Shoji, Masanori Emoto, Tsutomu Furuzono, Yoshiki Nishizawa, Masaaki Inaba
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329450?pdf=render