Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson’s Disease

Accumulation and misfolding of the alpha-synuclein protein are core mechanisms in the pathogenesis of Parkinson’s disease. While the normal function of alpha-synuclein is mainly related to the control of vesicular neurotransmission, its pathogenic effects are linked to various cellular functions, wh...

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Bibliographic Details
Main Authors: Wojciech Bobela, Patrick Aebischer, Bernard Laurent Schneider
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:Biomolecules
Subjects:
Online Access:http://www.mdpi.com/2218-273X/5/4/2675