Acute exercise modifies titin phosphorylation and increases cardiac myofilament stiffness

Acute exercise modifies titin phosphorylation and increases cardiac myofilament stiffness

Titin-based myofilament stiffness is largely modulated by phosphorylation of its elastic I-band regions N2-Bus (decreases passive stiffness, PT) and PEVK (increases PT). Here, we tested the hypothesis that acute exercise changes titin phosphorylation and modifies myofilament stiffness. Adult rats we...

Full description

Bibliographic Details
Main Authors: Anna Eliane Müller, Matthias eKreiner, Sebastian eKötter, Philipp eLassak, Wilhelm eBloch, Frank eSuhr, Martina eKrüger
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Physiology
Subjects:
heart muscle
skeletal muscle
posttranslational modification
Connectin
passive tension
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00449/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00449/full

Similar Items