Detection of UGT1A1*28 Polymorphism Using Fragment Analysis

Detection of UGT1A1*28 Polymorphism Using Fragment Analysis

Background and objective Uridine-diphosphoglucuronosyl transferase 1A1 (UGT1A1), UGT1A1*28 polymorphism can reduce UGT1A1 enzymatic activity, which may lead to severe toxicities in patients who receive irinotecan. This study tries to build a fragment analysis method to detect UGT1A1*28 polymorphism....

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Bibliographic Details
Main Authors: Ying HUANG, Jian SU, Xiaosui HUANG, Danxia LU, Zhi XIE, Suqing YANG, Weibang GUO, Zhiyi LV, Hongsui WU, Xuchao ZHANG
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2017-12-01
Series:Chinese Journal of Lung Cancer
Subjects:
UGT1A1
Fragment analysis
Polymorphism
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2017.12.04

Internet

http://dx.doi.org/10.3779/j.issn.1009-3419.2017.12.04

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