A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231

A novel tumor-activated ALA fusion protein for specific inhibition on the growth and invasion of breast cancer cells MDA-MB-231

Objective: The aim of this research was to develop a novel ALA fusion protein for target to the malignant cells surface with high uPAR expression and locally release of the scorpion toxin AGAP in an uPA-cleavable manner. It will provide an effective approach for controlled release of the peptide tox...

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Bibliographic Details
Main Authors: Xiufeng Liu, Xintong Liu, Suwen Sunchen, Meixia Liu, Chen Shen, Juanjuan Wu, Wanli Zhao, Boyang Yu, Jihua Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Drug Delivery
Subjects:
fusion protein
tumor activate
upa
agap
apoptosis
Online Access:http://dx.doi.org/10.1080/10717544.2017.1406560

Internet

http://dx.doi.org/10.1080/10717544.2017.1406560

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