Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis

Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis

There is an urgent need in multiple sclerosis (MS) patients to develop biomarkers and laboratory tests to improve early diagnosis, predict clinical relapses, and optimize treatment responses. In healthy individuals, the transport of proteins across the blood–brain barrier (BBB) is tightly regulated,...

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Bibliographic Details
Main Authors: Itay Raphael, Johanna Webb, Francisco Gomez-Rivera, Carol A. Chase Huizar, Rishein Gupta, Bernard P. Arulanandam, Yufeng Wang, William E. Haskins, Thomas G. Forsthuber
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Immunology
Subjects:
predictive biomarkers
multiple sclerosis
experimental autoimmune encephalomyelitis
T cell
central nervous system protein
serum expression
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00812/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00812/full

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