Mechanics and dynamics of X-chromosome pairing at X inactivation.

At the onset of X-chromosome inactivation, the vital process whereby female mammalian cells equalize X products with respect to males, the X chromosomes are colocalized along their Xic (X-inactivation center) regions. The mechanism inducing recognition and pairing of the X's remains, though, el...

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Bibliographic Details
Main Authors: Antonio Scialdone, Mario Nicodemi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2592697?pdf=render