Musashi–1—A Stemness RBP for Cancer Therapy?

The RNA–binding protein Musashi–1 (MSI1) promotes stemness during development and cancer. By controlling target mRNA turnover and translation, MSI1 is implicated in the regulation of cancer hallmarks such as cell cycle or Notch signaling. Thereby, the protein enhanced cancer growth and therapy resis...

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Bibliographic Details
Main Authors: Nadine Bley, Ali Hmedat, Simon Müller, Robin Rolnik, Alexander Rausch, Marcell Lederer, Stefan Hüttelmaier
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/5/407