Neuronal CCL2 expression drives inflammatory monocyte infiltration into the brain during acute virus infection
Abstract Background Viral encephalitis is a dangerous compromise between the need to robustly clear pathogen from the brain and the need to protect neurons from bystander injury. Theiler’s murine encephalomyelitis virus (TMEV) infection of C57Bl/6 mice is a model of viral encephalitis in which the c...
Main Authors: | Charles L. Howe, Reghann G. LaFrance-Corey, Emma N. Goddery, Renee K. Johnson, Kanish Mirchia |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2017-12-01
|
Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-017-1015-2 |
Similar Items
-
Disrupted spatial memory is a consequence of picornavirus infection
by: Eric J. Buenz, et al.
Published: (2006-11-01) -
Key role of the CCR2-CCL2 axis in disease modification in a mouse model of tauopathy
by: Hila Ben-Yehuda, et al.
Published: (2021-06-01) -
Inflammatory monocytes damage the hippocampus during acute picornavirus infection of the brain
by: Howe Charles L, et al.
Published: (2012-03-01) -
The role of picornavirus infection in epileptogenesis
by: Runxuan Zhang, et al.
Published: (2021-03-01) -
Implication des récepteurs de type Toll dans la migration des monocytes via la modulation du récepteur CCR7
by: Paradis, Alexandre
Published: (2015)