Generation of special autosomal dominant polycystic kidney disease iPSCs with the capability of functional kidney-like cell differentiation

Generation of special autosomal dominant polycystic kidney disease iPSCs with the capability of functional kidney-like cell differentiation

Abstract Background Human induced pluripotent stem cells (iPSCs) have been verified as a powerful cell model for the study of pathogenesis in hereditary disease. Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations of PKD or non-PKD genes. The pathogenesis of ADPKD remains une...

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Bibliographic Details
Main Authors: Jiahui Huang, Shumin Zhou, Xin Niu, Bin Hu, Qing Li, Feng Zhang, Xue Zhang, Xiujuan Cai, Yuanlei Lou, Fen Liu, Chenming Xu, Yang Wang
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Stem Cell Research & Therapy
Subjects:
Induced pluripotent stem cells
Autosomal-dominant polycystic kidney disease
Differentiation
Kidney cells
SAMSN1
Online Access:http://link.springer.com/article/10.1186/s13287-017-0645-8

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http://link.springer.com/article/10.1186/s13287-017-0645-8

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