TLR2/4 signaling pathway mediates sperm-induced inflammation in bovine endometrial epithelial cells in vitro.

We have recently shown that sperm attachment to bovine endometrial epithelial cells (BEECs) triggers uterine local innate immunity with induction of a pro-inflammatory response in vitro, however details of the mechanism remain unknown. Here, we investigated the involvement of Toll-like receptor 2/4...

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Bibliographic Details
Main Authors: Mohamed Aboul Ezz, Mohamed Ali Marey, Ahmed Essam Elweza, Tomoko Kawai, Maike Heppelmann, Christiane Pfarrer, Ahmed Zaky Balboula, Abdelmonem Montaser, Kazuhiko Imakawa, Samy Moawad Zaabel, Masayuki Shimada, Akio Miyamoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214516