Hesperidin produces cardioprotective activity via PPAR-γ pathway in ischemic heart disease model in diabetic rats.

The present study investigated the effect of hesperidin, a natural flavonoid, in cardiac ischemia and reperfusion (I/R) injury in diabetic rats. Male Wistar rats with diabetes were divided into five groups and were orally administered saline once daily (IR-sham and IR-control), Hesperidin (100 mg/kg...

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Bibliographic Details
Main Authors: Yogeeta O Agrawal, Pankaj Kumar Sharma, Birendra Shrivastava, Shreesh Ojha, Harshita M Upadhya, Dharamvir Singh Arya, Sameer N Goyal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4219710?pdf=render