High-Throughput Dissolution/Permeation Screening —A 96-Well Two-Compartment Microplate Approach

Early formulation screening can alleviate development of advanced oral drug formulations, such as amorphous solid dispersions (ASDs). Traditionally, dissolution is used to predict ASD performance. Here, a high-throughput approach is described that simultaneously screens drug dissolution and permeati...

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Bibliographic Details
Main Authors: Ann-Christin Jacobsen, Anna Krupa, Martin Brandl, Annette Bauer-Brandl
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/11/5/227