The PPARGC1A locus and CNS-specific PGC-1α isoforms are associated with Parkinson's Disease

The PPARGC1A locus and CNS-specific PGC-1α isoforms are associated with Parkinson's Disease

Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. PGC-1α, encoded by PPARGC1A, is a transcriptional co-activator that has been implicated in the pathogenesis of neurodegenerative disorders. We recently discovered multiple new PPARGC1A transcripts that initi...

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Bibliographic Details
Main Authors: Selma M. Soyal, Greta Zara, Boris Ferger, Thomas K. Felder, Markus Kwik, Charity Nofziger, Silvia Dossena, Christine Schwienbacher, Andrew A. Hicks, Peter P. Pramstaller, Markus Paulmichl, Serge Weis, Wolfgang Patsch
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
Lewy body dementia
PPARGC1A
PGC-1α
haplotypes
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996118305916

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http://www.sciencedirect.com/science/article/pii/S0969996118305916

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