Ligustrazine Inhibits Cartilage Endplate Hypertrophy via Suppression of TGF-β1

CEP hypertrophy is one of the characteristics of intervertebral disc degeneration (IDD). LIG exerts a protective effect on IDD in animal model. The effect of LIG on CEP hypertrophy is further investigated in the present study. Cells were isolated from hypertrophic samples obtained from patients duri...

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Bibliographic Details
Main Authors: Shufen Liu, Bizeng Zhao, Huipeng Shi, Qianqian Liang, Yishan Fu, Zhu Yang, Leqin Xu, Yongjun Wang, Qin Bian
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Evidence-Based Complementary and Alternative Medicine
Online Access:http://dx.doi.org/10.1155/2016/1042489