Synthesis, Characterization, and Anti-Cancer Activity of Some New N′-(2-Oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazones Derivatives

Synthesis, Characterization, and Anti-Cancer Activity of Some New N′-(2-Oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazones Derivatives

Eight novel N′-(2-oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazone derivatives 4a–h were synthesized and fully characterized by IR, NMR (1H-NMR and 13C-NMR), elemental analysis, and X-ray crystallography. The cyto-toxicity and in vitro anti-cancer evaluation of the prepared compounds have...

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Bibliographic Details
Main Authors: Ayman El-Faham, Muhammad Farooq, Sherine N. Khattab, Nael Abutaha, Mohammad A. Wadaan, Hazem A. Ghabbour, Hoong-Kun Fun
Format: Article
Language:English
Published: MDPI AG 2015-08-01
Series:Molecules
Subjects:
valproic acid
isatin
hydrazide-hydrazone
anti-cancer activity
Online Access:http://www.mdpi.com/1420-3049/20/8/14638

Internet

http://www.mdpi.com/1420-3049/20/8/14638

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