Urinary 8-oxo-7,8-dihydroguanosine as a Potential Biomarker of Aging

Urinary 8-oxo-7,8-dihydroguanosine as a Potential Biomarker of Aging

Background: A molecular biomarker of physiologic age, as opposed to chronologic age, is needed in clinical medicine. 8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodGsn) and 8-oxo-7, 8-dihydroguanosine (8-oxoGsn) are two promising aging biomarkers.Methods: A total of 1,228 healthy Chinese residents (613...

Full description

Bibliographic Details
Main Authors: Wei Gan, Xin-Le Liu, Ting Yu, Yuan-Gao Zou, Ting-Ting Li, Shuang Wang, Jin Deng, Lan-Lan Wang, Jian-Ping Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
8-oxoguanosine
urine
mass spectrometry
method validation
biomarkers of aging
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2018.00034/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2018.00034/full

Similar Items