Modeling key interactions between dopamine D2 receptor second extracellular loop and arylpiperazine ligands

Modeling key interactions between dopamine D2 receptor second extracellular loop and arylpiperazine ligands

Second extracellular loop (ecl2) of dopamine (DA) D2 receptor is an essential part of dopaminergic ligands binding pocket. To form a part of the ligand binding surface it has to fold down into the transmembrane domain of the DA receptor. The current study describes the modeling of the D2 DA recep...

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Bibliographic Details
Main Authors: Šukalović Vladimir, Šoškić Vukić, Andrić Deana, Roglić Goran, Kostić-Rajačić Slađana
Format: Article
Language:English
Published: Serbian Chemical Society 2012-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
extracellular loop
dopamine
arylpiperazine
molecular modeling
GPRC
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391100212S.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391100212S.pdf

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