Regulation of mTORC2 Signaling

Mammalian target of rapamycin (mTOR), a serine/threonine protein kinase and a master regulator of cell growth and metabolism, forms two structurally and functionally distinct complexes, mTOR complex 1 (mTORC1) and mTORC2. While mTORC1 signaling is well characterized, mTORC2 is relatively poorly unde...

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Bibliographic Details
Main Authors: Wenxiang Fu, Michael N. Hall
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
Akt
Online Access:https://www.mdpi.com/2073-4425/11/9/1045