Aminosugar-based immunomodulator lipid A: synthetic approaches
The immediate immune response to infection by Gram-negative bacteria depends on the structure of a lipopolysaccharide (LPS, also known as endotoxin), a complex glycolipid constituting the outer leaflet of the bacterial outer membrane. Recognition of picomolar quantities of pathogenic LPS by the germ...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Beilstein-Institut
2018-01-01
|
| Series: | Beilstein Journal of Organic Chemistry |
| Subjects: | |
| Online Access: | https://doi.org/10.3762/bjoc.14.3 |