Sex-Specific Regulation of Gene Expression Networks by Surfactant Protein A (SP-A) Variants in Alveolar Macrophages in Response to Klebsiella pneumoniae

Surfactant protein A (SP-A) in addition to its surfactant-related functions interacts with alveolar macrophages (AM), the guardian cells of innate immunity in the lungs, and regulates many of its functions under basal condition and in response to various pressures, such as infection and oxidative st...

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Bibliographic Details
Main Authors: Nithyananda Thorenoor, Yuka Imamura Kawasawa, Chintan K. Gandhi, Joanna Floros
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
TNF
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01290/full