Discovering conformational sub-states relevant to protein function.

Internal motions enable proteins to explore a range of conformations, even in the vicinity of native state. The role of conformational fluctuations in the designated function of a protein is widely debated. Emerging evidence suggests that sub-groups within the range of conformations (or sub-states)...

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Bibliographic Details
Main Authors: Arvind Ramanathan, Andrej J Savol, Christopher J Langmead, Pratul K Agarwal, Chakra S Chennubhotla
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3030567?pdf=render