Role of advanced glycation end products and sorbitol dehydrogenase in the pathogenesis of diabetic retinopathy

Role of advanced glycation end products and sorbitol dehydrogenase in the pathogenesis of diabetic retinopathy

Abstract Background Diabetic retinopathy is one of the common microvascular complications of diabetes. The formation of advanced glycation end products (AGE) exerts deleterious effects by acting directly to induce cross-linking of proteins promoting vascular damage. Hyperglycemia causes disturbance...

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Main Authors: Leqaa A. Moemen, Mona A. Abdel Hamid, Soher Abdel Wahab, Mahmoud Kenawy M. Kenawy, Manal H. Abuelela, Olfat A. Hassanin, Marwa A. Fouly, Amira A. Abdelazeem, Shahira Riad Noweir, Somaia M. Ismail, Yara Hossam Eldin R. Abdel Gawad, Safa Refaat, Azza K. Amer, Nervana A. Khalaf, Safya H. Aboelmakarem, Mehry S. Elsobky, Mona R. Abdelrasool, Sherif S. Karawya, Zeinab M. Osman
Format: Article
Language:English
Published: SpringerOpen 2020-04-01
Series:Bulletin of the National Research Centre
Subjects:
Advanced glycation end products
Sorbitol dehyderogenas
Diabetic retinopathy
Online Access:http://link.springer.com/article/10.1186/s42269-020-00304-0

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http://link.springer.com/article/10.1186/s42269-020-00304-0

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