Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens.

Mammalian host response to pathogenic infections is controlled by a complex regulatory network connecting regulatory proteins such as transcription factors and signaling proteins to target genes. An important challenge in infectious disease research is to understand molecular similarities and differ...

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Bibliographic Details
Main Authors: Deborah Chasman, Kevin B Walters, Tiago J S Lopes, Amie J Eisfeld, Yoshihiro Kawaoka, Sushmita Roy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1005013