Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner.

Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner.

Vaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important role in cell cycle regulation and its expression is altered in several human cancers. In mouse model, DUSP3 deletion prevents neo-angiogenesis and b-FGF-induced microvessel outgrowth. Considering the importance of a...

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Bibliographic Details
Main Authors: Maud Vandereyken, Sophie Jacques, Eva Van Overmeire, Mathieu Amand, Natacha Rocks, Céline Delierneux, Pratibha Singh, Maneesh Singh, Camille Ghuysen, Caroline Wathieu, Tinatin Zurashvili, Nor Eddine Sounni, Michel Moutschen, Christine Gilles, Cécile Oury, Didier Cataldo, Jo A Van Ginderachter, Souad Rahmouni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5636116?pdf=render

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http://europepmc.org/articles/PMC5636116?pdf=render

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