Screening and characterization of hypothetical proteins of Plasmodium falciparum as novel vaccine candidates in the fight against malaria using reverse vaccinology

Abstract Background Plasmodium falciparum is the most deadly and leading cause of morbidity and mortality in Africa. About 90% of all malaria deaths in the world today occur in Sub-Saharan Africa especially in children aged < 5 years. In 2018, it was reported that there were 228 million malaria c...

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Bibliographic Details
Main Authors: Claire Aguttu, Brenda Apio Okech, Ambrose Mukisa, George William Lubega
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:Journal of Genetic Engineering and Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s43141-021-00199-y