A serum microRNA signature predicts trastuzumab benefit in HER2-positive metastatic breast cancer patients
Resistance to therapy is a significant issue for patients with metastatic breast cancer (MBC). Here the authors analyze total miRNA from serum samples of 386 MBC patients before treatment with a follow up of 31 months and define a four miRNA signature that predicts the therapeutic benefit of trastuz...
Main Authors: | , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-04-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-03537-w |