The Clinical Significance of Iron Overload and Iron Metabolism in Myelodysplastic Syndrome and Acute Myeloid Leukemia

The Clinical Significance of Iron Overload and Iron Metabolism in Myelodysplastic Syndrome and Acute Myeloid Leukemia

Myelodysplasticsyndrome (MDS) and acute myeloid leukemia (AML) are clonal hematopoietic stem cell diseases leading to an insufficient formation of functional blood cells. Disease-immanent factors as insufficient erythropoiesis and treatment-related factors as recurrent treatment with red blood cell...

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Bibliographic Details
Main Authors: Sarah Weber, Anastasia Parmon, Nina Kurrle, Frank Schnütgen, Hubert Serve
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
myelodysplastic syndrome
acute myeloid leukemia
iron overload
reactive oxygen species
microenvironment
iron chelation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.627662/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2020.627662/full

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