Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model

Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model

Parkinson's disease (PD) is characterized by a selective loss of dopamine (DA) neurons in the human midbrain causing motor dysfunctions. The exact mechanism behind dopaminergic cell death is still not completely understood and, so far, no cure or neuroprotective treatment for PD is available. R...

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Bibliographic Details
Main Authors: Bárbara Mendes-Pinheiro, Sandra I. Anjo, Bruno Manadas, Jorge D. Da Silva, Ana Marote, Leo A. Behie, Fábio G. Teixeira, António J. Salgado
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Parkinson's disease
mesenchymal stem cells
secretome
dopamine neurons
neuroprotection
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00294/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00294/full

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