Thrombospondin 1 improves hepatic steatosis in diet-induced insulin-resistant mice and is associated with hepatic fat content in humans

Thrombospondin 1 improves hepatic steatosis in diet-induced insulin-resistant mice and is associated with hepatic fat content in humans

Background: Nonalcoholic fatty liver disease (NAFLD) is associated with altered production of secreted proteins. Increased understanding of secreted proteins could lead to improved prediction and treatment of NAFLD. Here, we aimed to discover novel secreted proteins in humans that are associated wit...

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Bibliographic Details
Main Authors: Jinyun Bai, Mingfeng Xia, Yaqian Xue, Fengguang Ma, Aoyuan Cui, Yixuan Sun, Yamei Han, Xi Xu, Feifei Zhang, Zhimin Hu, Zhengshuai Liu, Yuxiao Liu, Genxiang Cai, Weitong Su, Xiaoyang Sun, Haifu Wu, Hongmei Yan, Xinxia Chang, Xiqi Hu, Hua Bian, Pu Xia, Jing Gao, Yu Li, Xin Gao
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:EBioMedicine
Subjects:
Thrombospondin 1
CD36
Hepatic steatosis
NAFLD
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396420302243

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http://www.sciencedirect.com/science/article/pii/S2352396420302243

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