Chemoresistance to Cancer Treatment: Benzo-α-Pyrene as Friend or Foe?

Chemoresistance to Cancer Treatment: Benzo-α-Pyrene as Friend or Foe?

Background: Environmental pollution such as exposure to pro-carcinogens including benzo-α-pyrene is becoming a major problem globally. Moreover, the effects of benzo-α-pyrene (BaP) on drug pharmacokinetics, pharmacodynamics, and drug resistance warrant further investigation, espe...

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Bibliographic Details
Main Authors: Kevin Dzobo, Naseeha Hassen, Dimakatso Alice Senthebane, Nicholas Ekow Thomford, Arielle Rowe, Hendrina Shipanga, Ambroise Wonkam, M. Iqbal Parker, Shaheen Mowla, Collet Dandara
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Molecules
Subjects:
environmental pollution
benzo-α-pyrene
procarcinogen
esophageal cancer
cisplatin
5-fluorouracil
paclitaxel
chemoresistance
drug metabolizing enzymes
apoptosis
Online Access:http://www.mdpi.com/1420-3049/23/4/930

Internet

http://www.mdpi.com/1420-3049/23/4/930

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