Cytochrome c as a potentially clinical useful marker of mitochondrial and cellular damage

Mitochondria are evolutionary endosymbionts derived from bacteria. Thus they bear molecules, such as mitochondrial DNA that contains CpG DNA repeats and N-formyl peptides, found in bacteria. Upon cell necrosis or apoptosis these molecules are released into the interstitial space and the circulation...

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Bibliographic Details
Main Authors: Theodoros Eleftheriadis, Georgios Pissas, Vassilios Liakopoulos, Ioannis Stefanidis
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00279/full