Extracellular vesicles from regenerative human cardiac cells act as potent immune modulators by priming monocytes

Extracellular vesicles from regenerative human cardiac cells act as potent immune modulators by priming monocytes

Abstract Background Nano-sized vesicles, so called extracellular vesicles (EVs), from regenerative cardiac cells represent a promising new therapeutic approach to treat cardiovascular diseases. However, it is not yet sufficiently understood how cardiac-derived EVs facilitate their protective effects...

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Bibliographic Details
Main Authors: Christien M. Beez, Marion Haag, Oliver Klein, Sophie Van Linthout, Michael Sittinger, Martina Seifert
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Nanobiotechnology
Subjects:
Extracellular vesicles
Exosomes
Cardiac cells
Immunomodulation
CD14+ myeloid suppressive cells
Monocytes
Online Access:http://link.springer.com/article/10.1186/s12951-019-0504-0

Internet

http://link.springer.com/article/10.1186/s12951-019-0504-0

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