Identification of Potential Calorie Restriction-Mimicking Yeast Mutants with Increased Mitochondrial Respiratory Chain and Nitric Oxide Levels

Calorie restriction (CR) induces a metabolic shift towards mitochondrial respiration; however, molecular mechanisms underlying CR remain unclear. Recent studies suggest that CR-induced mitochondrial activity is associated with nitric oxide (NO) production. To understand the role of mitochondria in C...

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Bibliographic Details
Main Authors: Bin Li, Craig Skinner, Pablo R. Castello, Michiko Kato, Erin Easlon, Li Xie, Tianlin Li, Shu-Ping Lu, Chen Wang, Felicia Tsang, Robert O. Poyton, Su-Ju Lin
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Aging Research
Online Access:http://dx.doi.org/10.4061/2011/673185