Overview of Histone Deacetylase Inhibitors in Haematological Malignancies

Overview of Histone Deacetylase Inhibitors in Haematological Malignancies

Histone deacetylase inhibitors (HDACi) can induce hyperacetylation of both histone and non-histone target resulting in epigenetic reprogramming and altered activity, stability and localisation of non-histone proteins to ultimately mediate diverse biological effects on cancer cells and their microenv...

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Bibliographic Details
Main Authors: H. Miles Prince, Simon Harrison, Mark J. Bishton, Ricky W. Johnstone, Michael Dickinson
Format: Article
Language:English
Published: MDPI AG 2010-08-01
Series:Pharmaceuticals
Subjects:
Histone deacetylase inhibitors
Clinical studies
Haematology
Online Access:http://www.mdpi.com/1424-8247/3/8/2674/

Internet

http://www.mdpi.com/1424-8247/3/8/2674/

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