Dissecting genetic factors affecting phenylephrine infusion rates during anesthesia: a genome-wide association study employing EHR data

Dissecting genetic factors affecting phenylephrine infusion rates during anesthesia: a genome-wide association study employing EHR data

Abstract Background The alpha-adrenergic agonist phenylephrine is often used to treat hypotension during anesthesia. In clinical situations, low blood pressure may require prompt intervention by intravenous bolus or infusion. Differences in responsiveness to phenylephrine treatment are commonly obse...

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Bibliographic Details
Main Authors: Yanfei Zhang, S. Mark Poler, Jiang Li, Vida Abedi, Sarah A. Pendergrass, Marc S. Williams, Ming Ta Michael Lee
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Medicine
Subjects:
Phenylephrine
Anesthesia
Hypotension
GWAS
EDN2
Electronic health records (EHR)
Online Access:http://link.springer.com/article/10.1186/s12916-019-1405-7

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http://link.springer.com/article/10.1186/s12916-019-1405-7

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