Single-Cell Analysis Identifies Thymic Maturation Delay in Growth-Restricted Neonatal Mice

Single-Cell Analysis Identifies Thymic Maturation Delay in Growth-Restricted Neonatal Mice

Fetal growth restriction (FGR) causes a wide variety of defects in the neonate which can lead to increased risk of heart disease, diabetes, anxiety and other disorders later in life. However, the effect of FGR on the immune system, is poorly understood. We used a well-characterized mouse model of FG...

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Bibliographic Details
Main Authors: Wendi A. Bacon, Russell S. Hamilton, Ziyi Yu, Jens Kieckbusch, Delia Hawkes, Ada M. Krzak, Chris Abell, Francesco Colucci, D. Stephen Charnock-Jones
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
Drop-Seq
fetal growth restriction
T-cell
thymus
single-cell
developmental programming
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02523/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02523/full

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