Functional Heterogeneity of Mouse and Human Brain OPCs: Relevance for Preclinical Studies in Multiple Sclerosis

Functional Heterogeneity of Mouse and Human Brain OPCs: Relevance for Preclinical Studies in Multiple Sclerosis

Besides giving rise to oligodendrocytes (the only myelin-forming cell in the Central Nervous System (CNS) in physiological conditions), Oligodendrocyte Precursor Cells (OPCs) are responsible for spontaneous remyelination after a demyelinating lesion. They are present along the mouse and human CNS, b...

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Bibliographic Details
Main Authors: Ana Bribián, Eva M. Medina-Rodríguez, Fernando Josa-Prado, Isabel García-Álvarez, Isabel Machín-Díaz, Pedro F. Esteban, Verónica Murcia-Belmonte, Lorena Vega-Zelaya, Jesús Pastor, Leoncio Garrido, Fernando de Castro
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Journal of Clinical Medicine
Subjects:
oligodendrocyte
myelin
multiple sclerosis
human
remyelination
leukodystrophies
Online Access:https://www.mdpi.com/2077-0383/9/6/1681

Internet

https://www.mdpi.com/2077-0383/9/6/1681

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