Application of experimental design in examination of the dissolution rate of carbamazepine from formulations: Characterization of the optimal formulation by DSC, TGA, FT-IR and PXRD analysis

Application of experimental design in examination of the dissolution rate of carbamazepine from formulations: Characterization of the optimal formulation by DSC, TGA, FT-IR and PXRD analysis

Poor solubility is one of the key reasons for the poor bioavailability of these drugs. This paper displays a formulation of a solid surfactant system with carbamazepine, in order to increase its dissolution rate. Solid state surfactant systems are formed by application of fractal experiment...

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Bibliographic Details
Main Authors: Krstić Marko, Ražić Slavica, Vasiljević Dragana, Spasojević Đurđija, Ibrić Svetlana
Format: Article
Language:English
Published: Serbian Chemical Society 2015-01-01
Series:Journal of the Serbian Chemical Society
Subjects:
poloxamer
neusilin
diatomite
solid surfactant drug delivery systems
polymorphous transition
Online Access:http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400114K.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0352-5139/2015/0352-51391400114K.pdf

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