Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis.

Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis.

Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by excessive deposition of extracellular matrix (ECM).We investigated the regulation of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lung fibrosis.MMP and TIMP expression, collagenolytic activity and collagen co...

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Bibliographic Details
Main Authors: Takwi Nkyimbeng, Clemens Ruppert, Takayuki Shiomi, Bhola Dahal, György Lang, Werner Seeger, Yasunori Okada, Jeanine D'Armiento, Andreas Günther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3759404?pdf=render

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http://europepmc.org/articles/PMC3759404?pdf=render

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